Normal values of biochemical parameters in serum of New Zealand White Rabbits


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Özkan Ö., Pekkaya S.

Turk Hijyen ve Deneysel Biyoloji Dergisi, vol.76, no.2, pp.157-162, 2019 (Scopus) identifier

Abstract

© 2019, Refik Saydam National Public Health Agency (RSNPHA).Objective: Laboratory animals, which are an organ complex, are used as model for human in biomedical studies. For this reason, information about the normal physiological values of laboratory animals provide important information on their health status. In this study, it is aimed to determine the serum normal biochemical values of New Zealand rabbits. Methods: Blood was taken from the ears of 93 rabbits. Biochemical tests were performed on serum samples. For analyses, commercial diagnostic kits were used for determination of biochemical parameters. Statistically, the difference between the mean values of the variables according to male and female rabbit was analyzed by independent sample t-test. Results: Albumin, protein, CK (creatin kinase) and LDH (lactade dehydrogenase) (p < 0.05) values were found statistically significant between male and female rabbits. On the other hand, creatinine, cholesterol and Mg values (p < 0.05) increased significantly in female rabbits. Conclusion: Biochemical tests should be conducted at regular intervals to assess the health status of animals. Since many variables are linked, the animals used in the research should be based on the values of the control group on the same conditions.