Akademik Veri Yönetim Sistemi
AME Medical Journal, cilt.2024, sa.Online First, ss.253-255, 2024 (ESCI)
Background: In cases of systemic lupus erythematosus (SLE) neurological, cardiac, and renal involvement are among the most frequently encountered clinical challenges that may ultimately be life-threatening.
are among the most frequently encountered clinical challenges that may ultimately be life-threatening.
Rhabdomyolysis is a rare complication reported on a case-by-case basis in SLE. Therapeutic plasma
exchange (TPE) is being utilized increasingly to treat SLE, with encouraging results. In contrast, data on the
use of TPE in the treatment of rhabdomyolysis is scarce.
Case Description: Herein, we report a case of a 23-year-old woman with a history of SLE experiencing
complications involving her heart and kidneys. Despite previous treatments, she discontinued medications
due to psychosocial issues. Upon admission, she exhibited symptoms such as shortness of breath and edema.
Laboratory tests revealed organ damage and urinary Escherichia coli infection, while imagings showed lung
and heart abnormalities. Treatment included steroids, antibiotics, and oxygen therapy. Rhabdomyolysis
was diagnosed and treated with TPE. Her condition improved over 2 weeks, and she was dischargedBackground: In cases of systemic lupus erythematosus (SLE) neurological, cardiac, and renal involvement
Rhabdomyolysis is a rare complication reported on a case-by-case basis in SLE. Therapeutic plasma
exchange (TPE) is being utilized increasingly to treat SLE, with encouraging results. In contrast, data on the
use of TPE in the treatment of rhabdomyolysis is scarce.
Case Description: Herein, we report a case of a 23-year-old woman with a history of SLE experiencing
complications involving her heart and kidneys. Despite previous treatments, she discontinued medications
due to psychosocial issues. Upon admission, she exhibited symptoms such as shortness of breath and edema.
Laboratory tests revealed organ damage and urinary Escherichia coli infection, while imagings showed lung
and heart abnormalities. Treatment included steroids, antibiotics, and oxygen therapy. Rhabdomyolysis
was diagnosed and treated with TPE. Her condition improved over 2 weeks, and she was discharged
with a comprehensive medical regimen, including medications for lupus management and psychological
support. SLE complicated by rhabdomyolysis, a rare and potentially deadly condition. The patient had been
successfully treated using TPE, leading to recovery.
Conclusions: Rhabdomyolysis accompanying SLE is an uncommon situation that raises the risk of
morbidity and mortality. TPE is an effective and safe treatment option in SLE where there is an inadequate
response to the classical treatments, where the side effects of treatment agents were hazardous, or where
treatment agents are contraindicated.
with a comprehensive medical regimen, including medications for lupus management and psychological
support. SLE complicated by rhabdomyolysis, a rare and potentially deadly condition. The patient had been
successfully treated using TPE, leading to recovery.
Conclusions: Rhabdomyolysis accompanying SLE is an uncommon situation that raises the risk of
morbidity and mortality. TPE is an effective and safe treatment option in SLE where there is an inadequate
response to the classical treatments, where the side effects of treatment agents were hazardous, or where
treatment agents are contraindicated