Early effects of mild brain trauma on the cytoskeletal proteins neurofilament(160) and MAP(2), and the preventive effects of mexilitine

Caner, H; Can, ALP; Atalay, B; Erdogan, B; Albayrak, AH; Kilinc, K; Bavbek, M; Altinors, N

doi:10.1007/s00701-003-0209-9

Early effects of mild brain trauma on the cytoskeletal proteins neurofilament(160) and MAP(2), and the preventive effects of mexilitine

Caner H., Can A., Atalay B., Erdogan B., Albayrak A., Kilinc K., ...Daha Fazla

ACTA NEUROCHIRURGICA, cilt.146, sa.6, ss.611-621, 2004 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 146 Sayı: 6
Basım Tarihi: 2004
Doi Numarası: 10.1007/s00701-003-0209-9
Dergi Adı: ACTA NEUROCHIRURGICA
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.611-621
Anahtar Kelimeler: mild head injury, neurofilament protein (NF160), microtubule-associated protein-2 (MAP2), lipid peroxidation mexilitine, MICROTUBULE-ASSOCIATED PROTEINS, LIPID-PEROXIDATION, SPECTRIN PROTEOLYSIS, AXONAL INJURY, CALPAIN, MEXILETINE, EXPRESSION, ALPHA, PHASE, RISK
Ankara Üniversitesi Adresli: Evet

Özet

Objective. The aims were to investigate the early effects of graded, closed, mild head injury on neurofilament protein (NF160) and microtubule-associated protein-2 (MAP(2)) and to examine the levels of lipid peroxidation and the impact of mexilitine, inhibitor of lipid peroxidation, pretreatment on tissue damage.