Early effects of mild brain trauma on the cytoskeletal proteins neurofilament(160) and MAP(2), and the preventive effects of mexilitine


Caner H., Can A., Atalay B., Erdogan B., Albayrak A., Kilinc K., ...Daha Fazla

ACTA NEUROCHIRURGICA, cilt.146, sa.6, ss.611-621, 2004 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 146 Sayı: 6
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1007/s00701-003-0209-9
  • Dergi Adı: ACTA NEUROCHIRURGICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.611-621
  • Anahtar Kelimeler: mild head injury, neurofilament protein (NF160), microtubule-associated protein-2 (MAP2), lipid peroxidation mexilitine, MICROTUBULE-ASSOCIATED PROTEINS, LIPID-PEROXIDATION, SPECTRIN PROTEOLYSIS, AXONAL INJURY, CALPAIN, MEXILETINE, EXPRESSION, ALPHA, PHASE, RISK
  • Ankara Üniversitesi Adresli: Evet

Özet

Objective. The aims were to investigate the early effects of graded, closed, mild head injury on neurofilament protein (NF160) and microtubule-associated protein-2 (MAP(2)) and to examine the levels of lipid peroxidation and the impact of mexilitine, inhibitor of lipid peroxidation, pretreatment on tissue damage.