Adie Tonic Pupil Following COVID-19: A Case Report and Literature Review

Tetik D., ATİLLA H.

Neuro-Ophthalmology, 2025 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2025
  • Doi Numarası: 10.1080/01658107.2025.2559406
  • Dergi Adı: Neuro-Ophthalmology
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier
  • Anahtar Kelimeler: Adie pupil, anisocoria, COVID-19, denervation hypersensitivity, pilocarpine
  • Ankara Üniversitesi Adresli: Evet

Özet

Adie tonic pupil is a neuro-ophthalmological disorder characterized by a dilated pupil with poor response to light. While most cases are idiopathic; autoimmune diseases, vascular diseases, autonomic disorders, and infections such as COVID-19 have been found to be associated with Adie tonic pupil. We present a 39-year-old woman who developed unilateral Adie tonic pupil following COVID-19. Diagnosis was confirmed by pupillary constriction with dilute pilocarpine test, indicating denervation hypersensitivity. This case adds to the growing evidence of post-COVID-19 neurological complications and underscores the importance of considering Adie tonic pupil in patients presenting with anisocoria after viral infections, especially in the context of the COVID-19 pandemic.