An unusual case of vancomycin-related systemic reaction accompanied with severe thrombocytopenia mimicking pacemaker-related infective endocarditis: a case report and review of literature

CANDEMİR, BAŞAR; Acibuca, Aynur; Koca, Cigdem; Ozcan, Ozgur; Gerede, Menekse; TULUNAY KAYA, CANSIN

doi:10.1007/s10840-012-9738-6

An unusual case of vancomycin-related systemic reaction accompanied with severe thrombocytopenia mimicking pacemaker-related infective endocarditis: a case report and review of literature

CANDEMİR B., Acibuca A., Koca C., Ozcan O. U., Gerede M., TULUNAY KAYA C.

JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY, cilt.38, sa.2, ss.143-145, 2013 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Derleme
Cilt numarası: 38 Sayı: 2
Basım Tarihi: 2013
Doi Numarası: 10.1007/s10840-012-9738-6
Dergi Adı: JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.143-145
Anahtar Kelimeler: Implantable cardioverter defibrillator, Infective endocarditis, Hematoma, Vancomycin, Thrombocytopenia, DRUG-INDUCED THROMBOCYTOPENIA
Ankara Üniversitesi Adresli: Evet

Özet

Vancomycin is a glycopeptide antibiotic used in the prophylaxis and treatment of infections caused by Gram-positive resistant bacteria. In recent years, several cases of vancomycin-associated immune thrombocytopenia have been presented as case reports, but the real incidence of this side effect is still unknown. In this report, we would like to present a case during which we confronted with a great dilemma: urgent removal of whole defibrillator system due to highly suspected infective endocarditis or leaving the defibrillator in place and simply switching vancomycin to another antibiotic agent and wait.