Protective effects of vitamins E, B and C and L-carnitine in the prevention of cisplatin-induced ototoxicity in rats

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Tokgoz S. A., Vuralkan E., Sonbay N. D., Caliskan M., Saka C., BEŞALTI Ö., ...More

JOURNAL OF LARYNGOLOGY AND OTOLOGY, vol.126, no.5, pp.464-469, 2012 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 126 Issue: 5
• Publication Date: 2012
• Doi Number: 10.1017/s0022215112000382
• Journal Name: JOURNAL OF LARYNGOLOGY AND OTOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.464-469
• Keywords: Ototoxicity, Cisplatin, Ear, Inner, Antioxidants, Rat, INDUCED HEARING-LOSS, ALPHA-TOCOPHEROL, 4-METHYLTHIOBENZOIC ACID, GUINEA-PIGS, TOXICITY, EFFICACY, AGENTS, NEPHROTOXICITY, CHEMOTHERAPY, ANTIOXIDANTS
• Ankara University Affiliated: Yes

Abstract

Objective: This experimental study aimed to investigate the effects of vitamins E, B and C and L-carnitine in preventing cisplatin-induced ototoxicity.