Akademik Veri Yönetim Sistemi
ANKARA UNIVERSITESI VETERINER FAKULTESI DERGISI, cilt.56, sa.4, ss.263-267, 2009 (SCI-Expanded)
This in vitro study was aimed to determine the phytochemical properties and acute LD50 of oral administration of the extract of sainfoin (Onobrychis viciifolia) which is largely distributed in Turkey. The phytochemical properties of the sainfoin extract were determined presence of alkaloids, saponins, tannins, peptide/proteins, Sugars, amino acids, phenols and phenolic acid, choline and flavonoids. Sixty female and 60 male of total 120 numbers of wistar albino mice, 25-35g weight, approximately two months age were used to determine acute LD50 level of the sainfoin extract. Acute oral LD50 of sainfoin was found >= 19000 mg/kg for males and >= 20000 mg/kg for females and phytochemical analysis of the extract or plant showed the presence of tannins, amino acids, proteins, Sucrose, phenolic contents; but the presence of alkaloids, simple Sugars, saponins and choline were not observed. We concluded that the acute toxicity of the plant orally administered to mice was low, which suggested that animal can consume safely it.