In vitro antimicrobial, antioxidant, and antispasmodic activities and the composition of the essential oil of origanum acutidens (Hand.-Mazz.) Ietswaart

Goze I., Alim A., Cetinus S. A., Çetin A., Durmus N., ATAŞ A., ...More

Journal of Medicinal Food, vol.13, no.3, pp.705-709, 2010 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 3
  • Publication Date: 2010
  • Doi Number: 10.1089/jmf.2009.0094
  • Journal Name: Journal of Medicinal Food
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.705-709
  • Keywords: antimicrobial activity, antioxidant activity, antispasmodic activity, essential oil, Origanum acutidens
  • Ankara University Affiliated: Yes

Abstract

The radical scavenging, antimicrobial, and antispasmodic activities and the composition of Origanum acutidens (Hand.-Mazz.) Ietswaart (Order Labiatte) essential oil were evaluated in vitro. Gas chromatography/mass spectrometry analysis of the oil resulted in the identification of 20 compounds, representing 93.61% of the oil; carvacrol (65%) was the main component. The sample was also subjected to a screening for antioxidant activity by using the 1,1-diphenyl-2-picrylhydrazyl and β-carotene/linoleic acid assays. The essential oil exhibited strong antioxidant activity. Using the agar disk diffusion method, antimicrobial activities of the essential oils were determined for nine microorganisms; antimicrobial activity was shown against eight of them. O. acutidens oil exhibited spontaneous contractions in rat ileum at the 100% level at 0.1 mg/mL level. © 2010, Mary Ann Liebert, Inc. and Korean Society of Food Science and Nutrition.