The use of carbetocin in the treatment of maternal cannibalism in dogs

KOÇKAYA M., SALGIRLI DEMİRBAŞ Y.

JOURNAL OF VETERINARY BEHAVIOR-CLINICAL APPLICATIONS AND RESEARCH, cilt.40, ss.98-102, 2020 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.jveb.2020.10.004
  • Dergi Adı: JOURNAL OF VETERINARY BEHAVIOR-CLINICAL APPLICATIONS AND RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, Psycinfo, Veterinary Science Database
  • Sayfa Sayıları: ss.98-102
  • Anahtar Kelimeler: carbetocin, dog, maternal cannibalism, oxytocin, QT INTERVAL PROLONGATION, ACTING OXYTOCIN ANALOG, BEHAVIOR, STRESS, PREGNANCY, PREVENTION
  • Ankara Üniversitesi Adresli: Evet

Özet

Maternal cannibalism is a serious condition, which negatively affects the well-being of the puppies and the mother as well as the owner. Although this condition has been found to be related to low oxytocin (OXT) levels and administration of OXT was found to be effective for decreasing postpartum anxiety in humans, no treatment procedure was recommended for dogs yet. In this study, carbetocin, a synthetic analog for OXT, was used in 19 Kangal dogs with a previous history of maternal cannibalism. The same treatment procedure, that is, administration of carbetocin every 6 hours, was applied to all dogs for 10 days after the birth. As a result, none of the dogs showed abnormal maternal behavior toward their puppies during and after the treatment. No adverse effect of carbetocin was detected in any of the dogs. This study is the first to provide an effective treatment protocol for dogs displaying maternal cannibalism. (C) 2020 Elsevier Inc. All rights reserved.