Association between plasma asymmetrical dimethylarginine activity and saphenous vein graft disease in patients with coronary bypass

Cagirci G., Cay S., Karakurt O., Buyukterzi Z., YAZIHAN N., Kilic H., ...Daha Fazla

CORONARY ARTERY DISEASE, cilt.21, sa.1, ss.20-25, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 1
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1097/mca.0b013e328332a6da
  • Dergi Adı: CORONARY ARTERY DISEASE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.20-25
  • Anahtar Kelimeler: asymmetrical dimethylarginine, saphenous vein graft, NITRIC-OXIDE SYNTHASE, MEAN PLATELET VOLUME, SOLUBILIZED ADHESION MOLECULES, ENDOTHELIAL DYSFUNCTION, UNSTABLE ANGINA, ARTERY-DISEASE, POTENTIAL ROLE, SERUM-LEVELS, RISK-FACTOR, ADMA
  • Ankara Üniversitesi Adresli: Evet

Özet

Background Coronary vein graft disease is an important contributor to the morbidity after coronary artery bypass graft surgery. Graft occlusion is a serious complication, which limits the use of the saphenous vein as a coronary bypass conduit. Asymmetrical dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase and it reduces the bioavailability of nitric oxide and begets endothelial dysfunction. The goal of this study was to examine the association between plasma ADMA activity and saphenous vein graft disease.