Sulphasalazine-induced hypersensitivity syndrome

Saral S., AKAY B. N., ŞANLI H.

TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY, cilt.47, sa.2, ss.123-125, 2013 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 2
  • Basım Tarihi: 2013
  • Doi Numarası: 10.4274/turkderm.22590
  • Dergi Adı: TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.123-125
  • Anahtar Kelimeler: Hypersensitivity, HHV-6, sulphasalazine, hepatitis, TOXIC EPIDERMAL NECROLYSIS, INDUCED DRESS SYNDROME, SYSTEMIC SYMPTOMS, DRUG RASH, REACTIVATION, EOSINOPHILIA, FEATURES, DANGER
  • Ankara Üniversitesi Adresli: Evet

Özet

Drug-induced hypersensitivity syndrome (DIHS) is one of the most dangerous drug reactions. Mortality and morbidity is increased by consequent systemic organ involvement. Maculopapular eruptions are the most common lesions accompanying DIHS, however, the morphology of skin lesions may vary. The most common cause of DIHS is the use of aromatic anticonvulsant drugs. However, one must not forget that other drugs may also cause DINS. Early recognition of the condition is the most important step in the treatment. Herein, we present a case of DINS triggered by sulphasalazine and associated with pustular eruption and maculopapular eruption.