An overview on recent approaches for colonic drug delivery systems

Deljavan Ghodrati A., ÇOMOĞLU T.

Pharmaceutical Development and Technology, 2024 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1080/10837450.2024.2362353
  • Dergi Adı: Pharmaceutical Development and Technology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Business Source Elite, Business Source Premier, Chemical Abstracts Core, International Pharmaceutical Abstracts, MEDLINE
  • Anahtar Kelimeler: Colon, colonic diseases, colonic drug delivery systems, innovative methods, nanoparticles, nanoparticulate drug delivery technologies
  • Ankara Üniversitesi Adresli: Evet

Özet

Colon-targeted drug delivery systems have garnered significant interest as potential solutions for delivering various medications susceptible to acidic and catalytic degradation in the gastrointestinal (GI) tract or as a means of treating colonic diseases naturally with fewer overall side effects. The increasing demand for patient-friendly drug administration underscores the importance of colonic drug delivery, particularly through noninvasive methods like nanoparticulate drug delivery technologies. Such systems offer improved patient compliance, cost reduction, and therapeutic advantages. This study places particular emphasis on formulations and discusses recent advancements in various methods for designing colon-targeted drug delivery systems and their medicinal applications.