Comparison of exercise stress testing with dobutamine stress echocardiography and exercise technetium-99m isonitrile single photon emission computerized tomography for diagnosis of coronary artery disease


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Oguzhan A., Kisacik H., Ozdemir K., Altunkeser B., Durmaz T., Altinyay E., ...More

JAPANESE HEART JOURNAL, vol.38, no.3, pp.333-344, 1997 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 3
  • Publication Date: 1997
  • Doi Number: 10.1536/ihj.38.333
  • Journal Name: JAPANESE HEART JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.333-344
  • Keywords: dobutamine, exercise, stress echocardiography, technetium 99m isonitrile single-photon emission computed tomography, RADIONUCLIDE VENTRICULOGRAPHY, SCINTIGRAPHY, ANGIOGRAPHY, INFUSION, ANGINA
  • Ankara University Affiliated: Yes

Abstract

To compare the value of exercise electrocardiography with dobutamine stress echocardiography and exercise technetium-99m isonitrile single-photon emission computed tomography for coronary artery disease, 70 patients with either suspected or proven coronary artery disease underwent dobutamine stress echocardiography, exercise technetium-99m isonitrile single-photon emission computed tomography (mibi-SPECT) and treadmill exercise electrocardiography (EGG). Dobutamine echocardiography and exercise mibi-SPECT revealed a higher overall sensitivitiy than exercise testing (90 vs 57%, p < 0.001; 96 vs 57%, P < 0.001, respectively). Dobutamine stress echocardiography showed a higher specificity than both exercise mibi-SPECT and treadmill exercise electrocardiography (90 vs 71%, P > 0.05; 90 and 62% p < 0.05, respectively) but the difference between dobutamine stress echocardiography and exercise mibi-SPECT was not statistically significant. Diagnostic accuracy of dobutamine stress echocardiography and exercise mibi-SPECT was higher than that of exercise testing (90 vs 59%, P < 0.001; 89 vs 59%, P < 0.001, respectively).