Thrombospondin-1, vascular endothelial growth factor expression and microvessel density in renal cell carcinoma and their relationship with multifocality

Baltaci, S; Orhan, D; Gogus, ÇAĞATAY; Filiz, E; Tulunay, O; Gogus, O

doi:10.1016/s0302-2838(03)00192-1

Thrombospondin-1, vascular endothelial growth factor expression and microvessel density in renal cell carcinoma and their relationship with multifocality

Baltaci S., Orhan D., Gogus Ç. M., Filiz E., Tulunay O., Gogus O.

EUROPEAN UROLOGY, cilt.44, sa.1, ss.76-81, 2003 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 44 Sayı: 1
Basım Tarihi: 2003
Doi Numarası: 10.1016/s0302-2838(03)00192-1
Dergi Adı: EUROPEAN UROLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.76-81
Anahtar Kelimeler: renal cell carcinoma, multifocality, thrombospondin-1, vascular endothelial growth factor, CLINICAL-SIGNIFICANCE, TUMOR ANGIOGENESIS, CANCER, PROGRESSION, METASTASIS, STAGE, LUNG
Ankara Üniversitesi Adresli: Evet

Özet

Objective: To evaluate the relevance of microvessel density (MVD) and the angiogenic factors, vascular endothelial growth factor (VEGF, an important angiogenic factor in solid tumors) and thrombospondin-1 (TSP-1, a potent inhibitor of angiogenesis), to multifocality of renal cell carcinoma (RCC).