Thrombospondin-1, vascular endothelial growth factor expression and microvessel density in renal cell carcinoma and their relationship with multifocality

Baltaci S., Orhan D., Gogus Ç. M., Filiz E., Tulunay O., Gogus O.

EUROPEAN UROLOGY, cilt.44, sa.1, ss.76-81, 2003 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 1
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1016/s0302-2838(03)00192-1
  • Dergi Adı: EUROPEAN UROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.76-81
  • Anahtar Kelimeler: renal cell carcinoma, multifocality, thrombospondin-1, vascular endothelial growth factor, CLINICAL-SIGNIFICANCE, TUMOR ANGIOGENESIS, CANCER, PROGRESSION, METASTASIS, STAGE, LUNG
  • Ankara Üniversitesi Adresli: Evet

Özet

Objective: To evaluate the relevance of microvessel density (MVD) and the angiogenic factors, vascular endothelial growth factor (VEGF, an important angiogenic factor in solid tumors) and thrombospondin-1 (TSP-1, a potent inhibitor of angiogenesis), to multifocality of renal cell carcinoma (RCC).