Carcinosarcoma/sarcomatoid carcinoma of the urinary bladder with features of malignant fibrous histiocytoma: The role of p53 in growth of the tumor Malign fibröz histiyositom özellikleri taşıyan mesane karsinosarkoması/sarkomatoid karsinoması: Tümör gelişiminde p53'ün rolü

Tulunay Ö., Yalçinkaya A., SÜER E., Göǧüş Ç., Tangal S., Şafak M.

Turk Uroloji Dergisi, cilt.37, sa.2, ss.172-176, 2011 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 2
  • Basım Tarihi: 2011
  • Doi Numarası: 10.5152/tud.2011.033
  • Dergi Adı: Turk Uroloji Dergisi
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.172-176
  • Anahtar Kelimeler: Carcinosarcoma, Malignant fibrous histiocytoma, P53, Sarcomatoid carcinoma, Urinary bladder, Urothelial carcinoma
  • Ankara Üniversitesi Adresli: Evet

Özet

This is a report of a case of carcinosarcoma/sarcomatoid carcinoma (CS/SC) of the urinary bladder. The patient underwent multiple excisional biopsies of the urinary bladder. Following development of multiple lung metastases, the patient died at 21 months after diagnosis. This case represents a very rare example of CS/SC of the urinary bladder with a malignant fibrous histiocytoma component that was characterized by morphologic and immunohistochemical findings, and proves that CS/SC of the urinary bladder is a very aggressive neoplasm. Analysis of the tumor indicated that different factors other than p53 may be associated with the growth of this tumor.