Evaluation of the Effect of Different Doses of Butaphosphan and Cyanocobalamin Combination in Dairy Cattle with Subclinical Ketosis

ŞAHAL M., Deniz A., Vural R., KÜPLÜLÜ Ş., POLAT İ. M., ÇOLAKOĞLU E. Ç., ...Daha Fazla

KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI, cilt.23, sa.3, ss.349-356, 2017 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.9775/kvfd.2016.16651
  • Dergi Adı: KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.349-356
  • Anahtar Kelimeler: Beta hydroxybutyrate, Butaphosphan, Cyanocobalamin, Subclinical ketosis, Reproductive performance, BODY CONDITION SCORE, BETA-HYDROXYBUTYRATE, EARLY LACTATION, ABOMASAL DISPLACEMENT, FEED-INTAKE, DRY PERIOD, MILK-YIELD, COWS, HEALTH, BLOOD
  • Ankara Üniversitesi Adresli: Evet

Özet

This study was conducted to assess the effects of different doses of butaphosphan-cyanocobalamin combination onbody condition score (BCS), beta-hydroxybutyrate (BHBA) and reproductive parameters in cows with subclinical ketosis (SCK). Holstein-Friesen cows (n=544) were checked for BHBA concentration. Cows with SCK (n=53, BHBA ranging from 1.00 to 3.00 mmol/L) were assigned randomly to receive saline (C0, n= 18), 5 mL/100 kg BW (C5, n=18) or 10 mL/100 kg BW (C10, n=17) butaphosphan-cyanocobalamin combination. BHBA concentration was measured on d 0, 10, and 18 relative to treatment application. BCS was evaluated weekly until d 60 postpartum. For reproductive parameters cows were monitored until d 150 postpartum. The median reduction in blood BHBA concentrations was 28, 57, and 75% for C0, C5, and C10, respectively. NEFA and total bilirubin concentrations were significantly decreased in C10 group. The relative median change in BCS as compared to baseline was 17, 12, and 6% for C0, C5, and C10, respectively. Between d 15 and 25 postpartum uterine involution was completed in 44, 83, and 88% of cows in groups C0, C5, and C10, respectively. Interval from calving to first insemination in group C10 was shorter than control group. Overall pregnancy rate was not different among groups. In conclusion butaphosphan-cyanocobalamin combination decreased severity of hyperketonemia, stimulated uterine involution, shortened time to first insemination and increased pregnancy rate.