The Effect of Recombinant Growth Hormone Treatment in Children with Idiopathic Short Stature and Low Insulin-Like Growth Factor-1 Levels

ŞIKLAR Z., Kocaay P., Camtosun E., Isakoca M., Hacihamdioglu B., Erdeve S. S., ...Daha Fazla

JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, cilt.7, sa.4, ss.301-306, 2015 (SCI-Expanded, Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7 Sayı: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.4274/jcrpe.2111
  • Dergi Adı: JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.301-306
  • Anahtar Kelimeler: Final height, growth hormone treatment, idiopathic short stature, insulin-like growth factor deficiency, FINAL HEIGHT, TURKISH CHILDREN, IGF1 DEFICIENCY, GH, PREVALENCE, REFERENCES, EFFICACY, THERAPY
  • Ankara Üniversitesi Adresli: Evet

Özet

Objective: Idiopathic short stature (ISS) constitutes a heterogeneous group of short stature which is not associated with an endocrine or other identifiable cause. Some ISS patients may have varying degrees of insulin-like growth factor-1 (IGF-1) deficiency. Recombinant growth hormone (rGH) treatment has been used by some authors with variable results. Reports on long-term rGH treatment are limited.