The Effect of Recombinant Growth Hormone Treatment in Children with Idiopathic Short Stature and Low Insulin-Like Growth Factor-1 Levels

ŞIKLAR Z., Kocaay P., Camtosun E., Isakoca M., Hacihamdioglu B., Erdeve S. S., ...More

JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, vol.7, no.4, pp.301-306, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 4
  • Publication Date: 2015
  • Doi Number: 10.4274/jcrpe.2111
  • Journal Name: JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.301-306
  • Keywords: Final height, growth hormone treatment, idiopathic short stature, insulin-like growth factor deficiency, FINAL HEIGHT, TURKISH CHILDREN, IGF1 DEFICIENCY, GH, PREVALENCE, REFERENCES, EFFICACY, THERAPY
  • Ankara University Affiliated: Yes

Abstract

Objective: Idiopathic short stature (ISS) constitutes a heterogeneous group of short stature which is not associated with an endocrine or other identifiable cause. Some ISS patients may have varying degrees of insulin-like growth factor-1 (IGF-1) deficiency. Recombinant growth hormone (rGH) treatment has been used by some authors with variable results. Reports on long-term rGH treatment are limited.