Methylenetetrahydrofolate reductase 677 C-T and homocysteine levels in Turkish patients with pseudoexfoliation

---

Turacli M., Tekeli O., Ozdemir F., Akar N.

CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, cilt.33, sa.5, ss.505-508, 2005 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 33 Sayı: 5
• Basım Tarihi: 2005
• Doi Numarası: 10.1111/j.1442-9071.2005.01070.x
• Dergi Adı: CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.505-508
• Anahtar Kelimeler: genetic, glaucoma, homocysteine, methylene-tetrahydrofolate reductase, pseudoexfoliation, VASCULAR-DISEASE, PLASMA HOMOCYSTEINE, 5,10-METHYLENETETRAHYDROFOLATE REDUCTASE, EXFOLIATION SYNDROME, COMMON MUTATION, RISK FACTOR, HYPERHOMOCYSTEINEMIA, MANIFESTATION, GLAUCOMA, FOLATE
• Ankara Üniversitesi Adresli: Evet

Özet

Purpose: The 677 C-T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with hyperhomocysteinaemia. This study aimed to investigate the frequency of MTHFR 677 C-T polymorphism and homocysteine (Hcy) levels in Turkish patients with pseudoexfoliation (PEX).