Methylenetetrahydrofolate reductase 677 C-T and homocysteine levels in Turkish patients with pseudoexfoliation

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Turacli M., Tekeli O., Ozdemir F., Akar N.

CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, vol.33, no.5, pp.505-508, 2005 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 33 Issue: 5
• Publication Date: 2005
• Doi Number: 10.1111/j.1442-9071.2005.01070.x
• Journal Name: CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.505-508
• Keywords: genetic, glaucoma, homocysteine, methylene-tetrahydrofolate reductase, pseudoexfoliation, VASCULAR-DISEASE, PLASMA HOMOCYSTEINE, 5,10-METHYLENETETRAHYDROFOLATE REDUCTASE, EXFOLIATION SYNDROME, COMMON MUTATION, RISK FACTOR, HYPERHOMOCYSTEINEMIA, MANIFESTATION, GLAUCOMA, FOLATE
• Ankara University Affiliated: Yes

Abstract

Purpose: The 677 C-T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with hyperhomocysteinaemia. This study aimed to investigate the frequency of MTHFR 677 C-T polymorphism and homocysteine (Hcy) levels in Turkish patients with pseudoexfoliation (PEX).