The relationship between frailty and serum alpha klotho levels in geriatric patients

Polat Y., YALÇIN A., YAZIHAN N., Bahsi R., Surmeli D. M., Akdas S., ...Daha Fazla

ARCHIVES OF GERONTOLOGY AND GERIATRICS, cilt.91, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 91
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.archger.2020.104225
  • Dergi Adı: ARCHIVES OF GERONTOLOGY AND GERIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, ASSIA, Abstracts in Social Gerontology, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Psycinfo, Veterinary Science Database
  • Anahtar Kelimeler: Aging, Biomarkers, Frailty syndrome, Geriatric syndrome, Sarcopenia, GENE-EXPRESSION, OLDER-ADULTS, INFLAMMATION, DEPRESSION, ASSOCIATION, MOUSE, WOMEN
  • Ankara Üniversitesi Adresli: Evet

Özet

Background: Frailty is a medical syndrome resulting in loss of endurance, strength and physiological function. There is insufficient data to understand the process of frailty formation at the gene level, however one of the product of Klotho gene known as an anti-aging gene with many functions that prolong lifespan is alpha klotho protein. We aimed to investigate the relationship between frailty and the serum alpha klotho protein levels.