Peripheral blood T-lymphocyte and T-lymphocyte subset ratios before and after treatment in schizophrenia patients not taking antipsychotic medication
TURK PSIKIYATRI DERGISI, cilt.19, sa.1, ss.5-12, 2008 (SSCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 19 Sayı: 1
- Basım Tarihi: 2008
- Dergi Adı: TURK PSIKIYATRI DERGISI
- Derginin Tarandığı İndeksler: Social Sciences Citation Index (SSCI), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.5-12
- Anahtar Kelimeler: schizophrenic, immunity (cellular), T-lymphocytes, flow-cytometry, PSYCHIATRIC-DISORDERS, CELL SUBSETS, SERUM-LEVELS, IMMUNITY, NEUROLEPTICS, POPULATIONS, RECEPTOR, SYSTEM
- Ankara Üniversitesi Adresli: Evet
Özet
Objective: Immune system abnormalities in schizophrenia have been previously studied. According to the present point of view, an infection or autoimmune process might be occurring in the form of cellular and/or humoral immune system abnormalities in schizophrenia. Furthermore, several effects of antipsychotic medication on the immunological profile of schizophrenic patients have been demonstrated. The present study aimed to compare the total T-lymphocytes level and the T-lymphocyte subset ratios in schizophrenia patients not treated with antipsychotics and healthy controls. The relationship between disease duration, symptom severity, and treatment response and T-lymphocyte profiles were investigated.