Behcet's Syndrome Complicated with Pulmonary Artery Thrombosis: Response to Tocilizumab Treatment

ŞAHİN EROĞLU D., ÇOLAKLAR A., Ceran A., Sezer S., Torgutalp M., KINIKLI G.

AKTUELLE RHEUMATOLOGIE, cilt.46, sa.05, ss.485-488, 2021 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Sayı: 05
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1055/a-1400-2586
  • Dergi Adı: AKTUELLE RHEUMATOLOGIE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE
  • Sayfa Sayıları: ss.485-488
  • Anahtar Kelimeler: pulmonary artery thrombosis, tocilizumab, Behcet's syndrome, recanalization, VASCULAR INVOLVEMENT, DISEASE
  • Ankara Üniversitesi Adresli: Evet

Özet

Pulmonary artery involvement is a rare but deadly complication of Behcet's syndrome (BS). This article presents a male patient with BS complicated with Budd-Chiari syndrome and pulmonary artery thrombosis. The patient had recurrent pulmonary artery thrombosis resistant to several immunosuppressive drugs including high-dose glucocorticoids and the anti-TNF agent infliximab. Following multiple relapses, he was effectively treated with tocilizumab, which also achieved complete recanalization of the thrombosed arteries.