EXPRESSION OF ADHESION MOLECULES ON THE ENDOTHELIUM OF NORMAL TISSUE VESSELS AND VASCULAR TUMORS

KUZU I., BICKNELL R., FLETCHER C., GATTER K.

LABORATORY INVESTIGATION, cilt.69, sa.3, ss.322-328, 1993 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 69 Sayı: 3
  • Basım Tarihi: 1993
  • Dergi Adı: LABORATORY INVESTIGATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.322-328
  • Anahtar Kelimeler: ADHESION MOLECULES, TISSUE DISTRIBUTION, IMMUNOHISTOCHEMISTRY, MONOCLONAL-ANTIBODY, CELL-ADHESION, SEQUENCE SIMILARITY, LEUKOCYTE ADHESION, T-CELLS, ICAM-1, INFLAMMATION, PROTEIN, NEUTROPHILS, PLATELETS
  • Ankara Üniversitesi Adresli: Hayır

Özet

BACKGROUND: Endothelial cells are important in initiating adhesive processes between circulating cells and extracellular structures and changes in their distribution are believed to be important in many pathologic conditions. Since little is known about the detailed distribution of adhesion molecules in human endothelium in different sites and circumstances, the present study has undertaken a detailed analysis of 5 of the putative most important adhesion molecules on a wide range of normal tissue endothelium. We have compared this reactivity with that seen in a comprehensive range of vascular tumors both benign and malignant.