Synthesis and microbiological activity of some novel N-[2-(p-substitutedphenyl)-5-benzoxazolyl]-cyclohexyl carboxamide, -cyclohexyl acetamide and -cyclohexyl propionamide derivatives
FARMACO, cilt.57, sa.9, ss.771-775, 2002 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 57 Sayı: 9
- Basım Tarihi: 2002
- Dergi Adı: FARMACO
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Index Chemicus (IC)
- Sayfa Sayıları: ss.771-775
- Anahtar Kelimeler: 5-amide-substituted benzoxazoles, antibacterial activity, antifungal activity
- Ankara Üniversitesi Adresli: Evet
Özet
The synthesis and microbiological activity of a new series of N-[2-(p-substituted phenyl)-5-benzoxazolyl]-cyclohexyl carboxamide, -cyclohexyl acetamide and -cyclohexyl propionamide derivatives (4-11) is described. The in vitro microbiological activity of the compounds was determined against Gram-positive, Gram-negative bacteria and the yeast Candida albicans in comparison with standard drugs. Microbiological results indicated that the synthesized compounds possessed a broad spectrum of activity against the tested microorganisms. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.