Evaluation of combined therapeutic effects of hydrogen sulfide donor sodium hydrogen sulfide and phosphodiesterase type-5 inhibitor tadalafil on erectile dysfunction in a partially bladder outlet obstructed rat model

YILMAZ ORAL D., KAYA SEZGİNER E., Oztekin C. V., Bayatli N., LOKMAN U., GÜR S.

NEUROUROLOGY AND URODYNAMICS, cilt.39, sa.4, ss.1087-1097, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 4
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1002/nau.24333
  • Dergi Adı: NEUROUROLOGY AND URODYNAMICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.1087-1097
  • Anahtar Kelimeler: benign prostatic hyperplasia, erectile dysfunction, hydrogen sulfide, partial bladder outlet obstruction, tadalafil, NITRIC-OXIDE, PATHWAY
  • Ankara Üniversitesi Adresli: Evet

Özet

Aims To evaluate the impacts of hydrogen sulfide (H2S) donor, sodium hydrogen sulfide (NaHS), and phosphodiesterase type-5 inhibitor (PDE5i), tadalafil per se and their combination treatment on partial bladder outlet obstruction (PBOO)-induced erectile dysfunction (ED).