Ovarian aging and premature ovarian failure

ŞÜKÜR Y. E., Kıvançlı İ. B., ÖZMEN B.

Journal of the Turkish German Gynecology Association, cilt.15, sa.3, ss.190-196, 2014 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 3
  • Basım Tarihi: 2014
  • Doi Numarası: 10.5152/jtgga.2014.0022
  • Dergi Adı: Journal of the Turkish German Gynecology Association
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.190-196
  • Anahtar Kelimeler: Ovarian aging, Premature ovarian failure, Reproduction
  • Ankara Üniversitesi Adresli: Evet

Özet

© 2014, by the Turkish-German Gynecological Education and Research Foundation.Physiological reproductive aging occurs as a result of a decrease in the number and quality of oocytes in ovarian cortex follicles. Although the reason for the decrease in the quality of the pool and follicular oocytes is not fully understood, endocrine, paracrine, genetic, and metabolic factors are thought to be effective. Nowadays, in order to understand the mechanisms of ovarian aging, genomic research has gained importance. The effect of co-factors, such as telomerase and ceramide, in the ovarian aging process is only getting ascertained with new research studies. The most important tests in the assessment of ovarian aging are antral follicle count and anti-Mullerian hormone.