Infrapatellar fat pad-derived stem cell-based regenerative strategies in orthopedic surgery

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HURİ P., Hamsici S., Ergene E., HURİ G., Doral M. N.

Knee Surgery and Related Research, cilt.30, sa.3, ss.179-186, 2018 (Scopus) identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 30 Sayı: 3
  • Basım Tarihi: 2018
  • Doi Numarası: 10.5792/ksrr.17.061
  • Dergi Adı: Knee Surgery and Related Research
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.179-186
  • Anahtar Kelimeler: Fat pad, Knee, Stem cell
  • Ankara Üniversitesi Adresli: Evet

Özet

© 2018 KOREAN KNEE SOCIETY.Infrapatellar fat pad is a densely vascularized and innervated extrasynovial tissue that fills the anterior knee compartment. It plays a role in knee biomechanics as well as constitutes a source of stem cells for regeneration after knee injury. Infrapatellar fat pad-derived stem cells (IPFP-ASCs) possess enhanced and age-independent differentiation capacity as compared to other stem cells, which makes them a very promising candidate in stem cell-based regenerative therapy. The aims of this review are to outline the latest advances and potential trends in using IPFP-ASCs and to emphasize the advantages over other sources of stem cells for applications in orthopedic surgery.