Akademik Veri Yönetim Sistemi
International Journal of Pharmacy and Pharmaceutical Sciences, cilt.8, sa.1, ss.284-288, 2016 (Scopus)
© 2016 The Authors. Published by Innovare Academic Sciences Pvt Ltd.Objective: The aim of the study was to investigate the antioxidant activities, chlorogenic acid/rutin profiles, and bioactive compounds’ contents of the various extracts from Prangos uechtritzii Boiss. & Hausskn. and Prangos pabularia Lindl. Methods: The antioxidant capacities of the extracts were evaluated by various methods, including the plasma lipid peroxidation inhibitory, β-carotene/linoleic acid bleaching, free radical scavenging activity, and metal chelating activity assays. Chlorogenic acid and rutin contents of the extracts were determined qualitatively and quantitatively by high-performance liquid chromatography (HPLC). Total phenolic, β-carotene, and lycopene contents of the extracts were also determined. Results: In the assays, the methanol and the water extracts showed higher antioxidant activities than the acetone and ethyl acetate extracts. According to HPLC analysis, the richest extracts in terms of rutin and chlorogenic acid were determined as P. pabularia methanol extract (12.61±0.11 μg/mg) and P. uechtritzii methanol extract (4.76±0.12 μg/mg), respectively. Conclusion: It could be suggested that these Prangos species, especially the water extract of P. uechtritzii may be used a potential source of natural antioxidants for food and pharmacy industries.