A modified method for determination of hippuric acid in urine by HPLC

DUYDU Y., SÜZEN H. S., VURAL N., ERDEM N., UYSAL H.

Ankara Universitesi Eczacilik Fakultesi Dergisi, cilt.28, sa.1, ss.37-46, 1999 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 1
  • Basım Tarihi: 1999
  • Dergi Adı: Ankara Universitesi Eczacilik Fakultesi Dergisi
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.37-46
  • Anahtar Kelimeler: Hippuric acid, HPLC method, Urine
  • Ankara Üniversitesi Adresli: Evet

Özet

In the present study, a fast and simple HPLC method has been described to determine urinary hippuric acid (HA). This modified method has provided an excellent recovery (101.9%) and linearity (R2 = 0.9767) for HA in urine. The coefficient of variation (CV) was also calculated in order to determine the reproducibility of this method and an adequate value has been observed. The validity of the present method was also tested by using four urine samples collected from toluene exposed painters.