Akademik Veri Yönetim Sistemi
2nd International Conference on Acoustic Neuroma Surgery / 2nd European-Skull-Base-Society Congress, Paris, Fransa, 22 - 26 Nisan 1995, ss.533-540, (Tam Metin Bildiri)
Surgery for malignant tumors of the skull base has a high risk of leaving microscopic disease and, thus, less chance of achieving a cure, and may result in serious postoperative complications, cranial nerve deficits and cosmetic deformities. The question of whether the results justify the risks of surgery still remains to be answered. In this study, between August 1992 and September 1994. a single team operated on 16 patients with malignant tumors of the skull base; six patients had primary tumors and ten had recurrent tumors. The types of tumor treated were six squamous cell carcinomas, four invasive basal cell carcinomas, three adenoid cystic carcinomas, one acinic cell carcinoma and two sarcomas. Radical tumor resection could be achieved in 14 patients; however, in two patients macroscopic tumor was left in the contralateral cavernous sinus in order not to endanger the patient with life-threatening complications. Reconstruction of the facial skin and skeleton was done satisfactorily using local flaps, pedicled flaps and free vascularized flaps. Postoperative complications were permanent facial nerve palsy and temporary cerebrospinal fluid leakage in one patient, and partial flap necrosis in three patients. The patients in this series had an overall survival rate of 81% for the mean follow-up period of 13 months and ultimate local control was accomplished in 69% of the cases. The results indicate that surgery for malignant tumors of the skull base improves the control of local disease and may provide extended periods of palliation.