Carotid intima-media thickness and ACE-gene polymorphism in hemodialysis patients


Nergizoglu G., KEVEN K., Gurses M., Aras O., ERTÜRK Ş., Duman N., ...More

JOURNAL OF NEPHROLOGY, vol.12, no.4, pp.261-265, 1999 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 4
  • Publication Date: 1999
  • Journal Name: JOURNAL OF NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.261-265
  • Keywords: ACE-gene, atherosclerosis, carotid intima-media thickness, hemodialysis, ANGIOTENSIN-CONVERTING ENZYME, INSERTION DELETION POLYMORPHISM, LEFT-VENTRICULAR HYPERTROPHY, MYOCARDIAL-INFARCTION, ARTERIAL-WALL, ATHEROSCLEROSIS, HEART
  • Ankara University Affiliated: Yes

Abstract

Background: Carotid artery intima-media thickness (CIMT) has been used as a marker of atherosclerosis. An insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene is associated,vith various cardiovascular diseases. This study is aimed at evaluating early atherosclerotic involvement of carotid vessels and the relation to known risk factors and ACE gene I/D in hemodialysis (HD) patients.