Severe Dry Eye in CD25 Deficiency Syndrome

Bas Z., Bayraktutar B. N., Ucakhan Ö. Ö.

EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE, cilt.44, sa.1, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1097/icl.0000000000000346
  • Dergi Adı: EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: CD25 deficiency, Dry eye, Ocular surface, Topical cyclosporin A, Meibomian gland dysfunction, GLAND DYSFUNCTION, ALPHA-CHAIN, CORNEAL, EXPRESSION, PHENOTYPE, MUTATION, MICE
  • Ankara Üniversitesi Adresli: Evet

Özet

CD25 deficiency (Interleukin-2 receptor alpha deficiency) is a rare subtype of combined B- and T-cell immunodeficiency. Recurrent infections and lymphocyte infiltration of multiple tissues are the main clinical presentations. Only four patients have been reported in whom ophthalmological findings were not described. In this article, ocular findings of CD25 deficiency in a 12-year-old child are highlighted.