Concurrent cystic mediastinal lymphangioma and paratesticular rhabdomyosarcorna
PEDIATRIC BLOOD & CANCER, vol.43, no.2, pp.156-158, 2004 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 43 Issue: 2
- Publication Date: 2004
- Doi Number: 10.1002/pbc.20081
- Journal Name: PEDIATRIC BLOOD & CANCER
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.156-158
- Keywords: cystic mediastinal lymphangioma, P53 gene, rhabdomyosarcoma, CHILDHOOD RHABDOMYOSARCOMA, P53 MUTATIONS, CHILDREN, FREQUENCY, THERAPY, OK-432
- Ankara University Affiliated: Yes
Abstract
The Current report describes a 23-month-old boy with paratesticular rhabdomyosarcoma who was incidentally diagnosed as also having an isolated mediastinal cystic lymphangioma. The association of childhood rhabdomyosarcoma with various congenital anomalies and genetic alterations such as p53 mutations have been well known. However, mediastinal cystic lymphangioma has not been reported among the congenital anomalies diagnosed in rhabdomyosarcoma. Both rhabdomyosarcoma and lymphangioma originate from mesenchymal cells. This association may be coincidental or may point to a common genetic and/or developmental disorder of the mesencymal tissue. (C) 2004 Wiley-Liss, Inc.