Relationship between age of menopause and cell-mediated immune hypersensitivity in right- and left-handed women

Dane Ş., KUMTEPE Y., Pasinlioglu T., Aksoy A.

International Journal of Neuroscience, cilt.114, sa.5, ss.651-657, 2004 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 114 Sayı: 5
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1080/00207450490430516
  • Dergi Adı: International Journal of Neuroscience
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.651-657
  • Anahtar Kelimeler: Handedness, Immunity, Menopause, Women
  • Ankara Üniversitesi Adresli: Evet

Özet

The aim of this work was to study the relationship between age of menopause and cell-mediated immune hypersensitivity in right- (N = 32) and left-handed (N = 15) women who had experienced menopause after age of 34 at least one year before interview. Age of menopause was higher in right-handed than left-handed women. Cell-mediated immunity was higher in left-handers than right-handers. Hand-preference correlated with age of menopause, but inversely correlated with tuberculin reaction and percentages of CD4+ and CD8+ lymphocytes; age of menopause correlated with cell-mediated immunity. The results suggested that early menopause in left-handed women may be due to a more active immune system, especially cell-mediated immunity.