Akademik Veri Yönetim Sistemi
19th International Nanoscience and Nanotechnology Conference (NanoTR-19), Ankara, Türkiye, 27 - 29 Ağustos 2025, ss.189, (Özet Bildiri)
The mouth is one of the primary entry points for microorganisms, where they can live and spread to other parts of the body. Teeth, with their nerves and
blood supply, provide a favorable environment for bacterial colonization. Over time, if proper precautions are not taken, bacteria can easily adhere to tooth
surfaces, leading to plaque formation. Gradually, they invade deeper structures, penetrate the root canals, and cause tooth decay. In terms of treatment, the
most effective approach is the removal of the infected tissue. At this point, root canal treatment becomes essential, as it involves removing the living blood
and nerve tissues, along with the decayed portions of the tooth, while preserving the healthy parts. The cleaned canals are then filled with adhesives and
gutta-percha. In this way, patients can continue using their natural teeth without the need for implants. However, in some cases, bacteria are difficult to
eradicate completely and may repopulate any openings they find, leading to secondary infections. Re-infection occurs when the main filling material,
gutta-percha, loses its integrity, and the adhesive cements begin to degrade, causing gutta-percha to detach from the tooth structure. The reappearance of
infection necessitates a repeat of the root canal treatment. This is often due to the survival of bacteria that are already resistant to most medications and
disinfectants. Therefore, the main aim of this study was to develop antibacterial surface coatings for gutta-percha. To achieve this, triclosan (TCS) was
selected as the material due to its proven antibacterial and antifungal properties and its widespread use in dental applications. In the study, thin films were
synthesized using the chemical vapor deposition (CVD) method with pressure range between 100 - 120 mTorr. The vaporized chemicals were applied to
ionized gutta-percha surfaces, where film formation occurred. Following polymerization, the films were tested for their antibacterial activity against
Escherichia coli and Staphylococcus epidermidis. FT-IR analysis confirmed the polymeric structure of the films such as main functional groups of benzene
rings were preserved while polymerization took place from -C-Cl, -C-N, -C=N and -OH groups. Bacterial colony analysis demonstrated their antibacterial
effectiveness over 15 days. The thin films significantly reduced the number of live bacterial colonies on the gutta-percha surfaces, achieving an inhibition
rate of 91.23–99.86% from day 1 to day 15 compared to reference uncoated gutta perchas.