Platelet aggregation in term and preterm newborns

UÇAR T., Gurman C., Arsan S., Kemahli S.

PEDIATRIC HEMATOLOGY AND ONCOLOGY, cilt.22, sa.2, ss.139-145, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 2
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1080/08880010590907230
  • Dergi Adı: PEDIATRIC HEMATOLOGY AND ONCOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.139-145
  • Anahtar Kelimeler: hemostasis, newborn, platelet aggregation, platelets, preterm, INTRAVENTRICULAR HEMORRHAGE, NEONATAL PLATELETS, BLOOD, INFANTS, BIRTH, HYPOREACTIVITY, BEHAVIOR
  • Ankara Üniversitesi Adresli: Evet

Özet

The platelets of newborns have a hyporeactive period. This period,, during which the platelet count is normal but their Junctions are deficient, is called transient platelet hyporeactivity of newborns. The platelet junctions and their normalizing process of term and preterm neonates are investigated. Twenty term and 20 preterm (gestational age <37 weeks) newborns were enrolled in the study. Twenty-eight healthy children aged 2 months to 3 years old participated in the study as the control group. Healthy newborns were followed for 15 days after birth longitudinally in, 3 periods: period 1 (0-4 days), period 2 (5-9 days), period 3 (10-15 days). Aggregation studies were performed from whole blood samples. Whole, blood, aggregation was measured by the impedance method. Transient. hyporeactivity of platelets was found in term and preterm groups, and there was no difference between term and preterms. Platelets of newborns gained their normal functions at postnatal 10-14 days. The results show that, hyporeactivity of platelets during the first 9 days of lips is physiological and transient.