Unveiling the Role of Human Papillomavirus in Urogenital Carcinogenesis a Comprehensive Review

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KARAOĞLAN B. B., ÜRÜN Y.

Viruses, cilt.16, sa.5, 2024 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 16 Sayı: 5
  • Basım Tarihi: 2024
  • Doi Numarası: 10.3390/v16050667
  • Dergi Adı: Viruses
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database, Directory of Open Access Journals
  • Anahtar Kelimeler: anal cancer, bladder cancer, HPV, Human papillomavirus, kidney cancer, male health, oncogenic virus, penile cancer, prostate cancer, renal cell carcinoma, testicular cancer, urogenital cancers, vaccine
  • Ankara Üniversitesi Adresli: Evet

Özet

Human papillomavirus (HPV), an oncogenic DNA virus, is the most common sexually transmitted virus and significant public health concern globally. Despite the substantial prevalence of HPV infection among men, routine testing remains elusive due to the lack of approved HPV tests and the complexity of detection methods. Various studies have explored the link between HPV and genitourinary cancers, revealing different associations influenced by geographic variation, histological subtype and methodological differences. These findings underscore the importance of further research to elucidate the role of HPV in male urogenital cancers. This comprehensive review delves into the intricate relationship between HPV and male genitourinary cancers, shedding light on the virus’s oncogenic mechanisms and its reported prevalence. A deeper understanding of HPV’s implications for male health is essential for advancing public health initiatives and reducing the burden of urogenital cancers worldwide.