Solid electrodes in electroanalytical chemistry: Present applications and prospects for high throughput screening of drug compunds

Uslu B., ÖZKAN S. A.

COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, cilt.10, sa.7, ss.495-513, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 10 Sayı: 7
  • Basım Tarihi: 2007
  • Doi Numarası: 10.2174/138620707782152425
  • Dergi Adı: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.495-513
  • Anahtar Kelimeler: solid electrodes, voltammetry, electroanalytical screening, drugs, biological media, supramolecular surface phenomena, BORON-DOPED DIAMOND, CARBON-PASTE ELECTRODE, PULSE VOLTAMMETRIC DETERMINATION, ION-SELECTIVE ELECTRODES, PHARMACEUTICAL DOSAGE FORMS, FLOW-INJECTION ANALYSIS, PRINTED ELECTROCHEMICAL SENSORS, ANODIC-STRIPPING VOLTAMMETRY, ZEOLITE-MODIFIED ELECTRODES, SILDENAFIL CITRATE VIAGRA
  • Ankara Üniversitesi Adresli: Evet

Özet

This review summarizes recent progress in the development and application of solid electrodes to the screening of pharmaceutical dosage forms and biological fluids. Recent trends and advances in the electroanalytical chemistry of solid electrodes, microelectrodes and electrochemical sensors are reviewed. The varieties of solid electrodes and their basic physico-chemical properties and some specific characteristics including some supramolecular phenomena at their surfacc are surveyed. This review also includes some selected designs and their applications. Despite many reviews about individual solid electrodes in the literature, this review offers the first comprehensive report on all forms of solid electrodes. Special attention is paid to the possibilities of solid electrodes in high throughput electroanalytical investigation of drug dosage forms and biological samples using modern electroanalytical techniques. Various selected studies on these subjects since 1996 are reviewed in this paper.