Akademik Veri Yönetim Sistemi
21st Congress of the ESRS , Paris, Fransa, 4 - 08 Eylül 2012, ss.291-292
Objective: To compare polysomnographic and demographic characteristics
of obstructive sleep apnea (OSA) patients with or without
excessive sleepiness assessed by Epworth sleepiness scale (ESS).
Method: Eighty-two adult patients (28 F, 54 M) with a diagnosis of
OSAS by polysomnography (AHI > 15 /h) were retrospectively
assessed in two groups in respect of presence (ESS > 10) or
absence (ESS < 10) of excessive daytime sleepiness (EDS) according
to ESS score.
Results: Forty-six patients had an ESS score >10. OSAS patients
with daytime sleepiness were younger (P = 0.01) and their arousal
index and apnea hypopnea index (AHI) were higher (P = 0.017 and
0.042, respectively). Although statistically non-significant, OSAS
patients with EDS were more obese and their sleep latency and
sleep efficiency in polysomnography were lower. In addition, in
OSAS patients with EDS the superficial sleep phase (NREM 1–2)
was more whereas deep slow sleep (NREM 3), REM sleep, and
average oxygen saturation at sleep were lower (P > 0.05). Thirty of
patients with EDS (65.1%) had nocturnal oxygen desaturation while
the same value in the group without EDS was 58.3%. In multiple
regression analysis the arousal index, total AHI, and age were all
effective in determination of ESS score (P = 0.002). As a result,
OSAS patients with EDS have a more severe disease, with a worse
sleep-associated respiratory pattern and more fragmented sleep
compared to OSAS patients without EDS. Rather than a single factor,
factors such as severity of OSAS, arousal index, and age are
determinants of ESS score that demonstrates the presence of EDS