Iatrogenic Cushing syndrome due to nasal steroid drops

Bas V. N., Cetinkaya S., AYCAN Z.

EUROPEAN JOURNAL OF PEDIATRICS, vol.171, no.4, pp.735-736, 2012 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 171 Issue: 4
  • Publication Date: 2012
  • Doi Number: 10.1007/s00431-011-1645-9
  • Journal Name: EUROPEAN JOURNAL OF PEDIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.735-736
  • Keywords: Cushing syndrome, Nasal steroids
  • Ankara University Affiliated: No

Abstract

Iatrogenic Cushing syndrome may occur as an undesirable outcome of high-dose glucocorticoids treatments. This may also cause hypothalamus-hypophysis-adrenal axis suppression. While this situation may be caused more frequently with oral and topical glucocorticoid therapy, iatrogenic Cushing syndrome in childhood, caused by steroid-containing nasal drops, is a rare event. Hereby, we present a baby who developed iatrogenic Cushing syndrome induced by long-term use of steroid-containing nasal drops for choanal atresia. In conclusion, the serious side effects of the nasal drops should have been explained to the family, and their long-term use should have been refrained.