A Case of Superwarfarin Poisoning Due to Repetitive Occupational Dermal Rodenticide Exposure in a Worker

Ozdemir Z. N., Sahin U., Merter M., Gunduz M., Atesagaoglu B., BEKSAÇ M.

TURKISH JOURNAL OF HEMATOLOGY, cilt.33, sa.3, ss.251-253, 2016 (SCI-Expanded, Scopus, TRDizin) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 3
  • Basım Tarihi: 2016
  • Doi Numarası: 10.4274/tjh.2015.0433
  • Dergi Adı: TURKISH JOURNAL OF HEMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.251-253
  • Anahtar Kelimeler: Superwarfarin, Acquired coagulopathies, Vitamin K, ANTICOAGULANT RODENTICIDES
  • Ankara Üniversitesi Adresli: Evet

Özet

Superwarfarin poisoning is usually due to chronic occult small-dose exposures and can easily be misdiagnosed and may lead to serious complications. The diagnosis can be confirmed by a concordant history and analyses of blood and urine specimens with the liquid chromatography with tandem mass spectrometry (LC-MS/MS) technique. Several months of continuous treatment with high doses of daily oral vitamin K, as well as other supportive measures, are warranted, especially when repeated laboratory measurements to help predict the treatment period are not available. In this paper, a case of superwarfarin poisoning due to chronic repetitive occupational dermal exposure to commercial rodenticides is presented.