The Effects of in vitro Hyperglycemic Incubation on A23187-Mediated Contractile Responses of Rat Thoracic Aorta
GAZI MEDICAL JOURNAL, cilt.30, sa.1, ss.35-38, 2019 (ESCI, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 30 Sayı: 1
- Basım Tarihi: 2019
- Doi Numarası: 10.12996/gmj.2019.09
- Dergi Adı: GAZI MEDICAL JOURNAL
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
- Sayfa Sayıları: ss.35-38
- Anahtar Kelimeler: Diabetes mellitus, Vascular smooth muscle, Endothelium, Hyperglycemia, Aging, ENDOTHELIUM-DEPENDENT CONTRACTIONS, OXIDATIVE STRESS, ACETYLCHOLINE, CALCIUM, COMPLICATIONS, HYPERTENSION, RELAXATION, RECEPTORS, ACID, WALL
- Ankara Üniversitesi Adresli: Evet
Özet
Objective: Vascular tonus has been controlled by several factors secreted from endothelium in physiological conditions. In the present study, the possible changes on endothelium-derived contractile responses in normoglycemic and hyperglycemic conditions in terms of exposure-time dependency has been investigated.