The Effects of in vitro Hyperglycemic Incubation on A23187-Mediated Contractile Responses of Rat Thoracic Aorta

ÖZAKCA GÜNDÜZ I.

GAZI MEDICAL JOURNAL, cilt.30, sa.1, ss.35-38, 2019 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.12996/gmj.2019.09
  • Dergi Adı: GAZI MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.35-38
  • Anahtar Kelimeler: Diabetes mellitus, Vascular smooth muscle, Endothelium, Hyperglycemia, Aging, ENDOTHELIUM-DEPENDENT CONTRACTIONS, OXIDATIVE STRESS, ACETYLCHOLINE, CALCIUM, COMPLICATIONS, HYPERTENSION, RELAXATION, RECEPTORS, ACID, WALL
  • Ankara Üniversitesi Adresli: Evet

Özet

Objective: Vascular tonus has been controlled by several factors secreted from endothelium in physiological conditions. In the present study, the possible changes on endothelium-derived contractile responses in normoglycemic and hyperglycemic conditions in terms of exposure-time dependency has been investigated.