Synthesis of some new N-isopropylamidinobibenzimidazoles as potential topoisomerase inhibitors

KUŞ C., Boykin D. W., GÖKER A. H.

Heterocyclic Communications, cilt.8, sa.3, ss.215-220, 2002 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 3
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1515/hc.2002.8.3.215
  • Dergi Adı: Heterocyclic Communications
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.215-220
  • Ankara Üniversitesi Adresli: Evet

Özet

N-Isopropyl-2-[4-(1-methyl-1H-benzimidazol-2-yl)-phenyl]-1H-benzimidazole-5- carboxamidine (3), 2'-(4-fluorophenyl)-N-isopropyl-1'-methyl-1H,1'H-[2,5']-bibenzimidazolyl-5- carboxamidine(7) and 1'-butyl-N-isopropyl-2'-{4-[5-(N-isopropyl-carbamimidoyl)-1H-benzimidazol-2 -yl]phenyl}-1H,1'H-[2,5'] bibenzimidazolyl-5-carboxamidine (9) have been synthesized.