Molecular analysis of mycobacterial DNA in some cases of sarcoidosis: Correlation with clinical course and 10 years' observation Bazi Sarkoidoz Vakalarında Mikobakteriyel DNA'nın Moleküler Analizi: Klinik Yönü ile Iliskisi ve 10 Yıllık Gözlem

Kurtuluş Ülküer M., ÖZDEMİR KUMBASAR Ö., ÇELİK G.

Turkish Journal of Pharmaceutical Sciences, cilt.7, sa.2, ss.189-195, 2010 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7 Sayı: 2
  • Basım Tarihi: 2010
  • Dergi Adı: Turkish Journal of Pharmaceutical Sciences
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.189-195
  • Anahtar Kelimeler: Clinical course, M. tuberculosis, Polymerase chain reaction, Sarcoidosis
  • Ankara Üniversitesi Adresli: Evet

Özet

We present six patients with sarcoidosis whose transbronchial biopsy specimens had been investigated, the gene of immunogenic protein MPB64 for Mycobacterium tuberculosis by polymerase chain reaction analysis. M. tuberculosis DNA was detected in three of them by PCR. We followed patients with sarcoidosis for ten years. We discussed tuberculin test results and clinical course of M. tuberculosis positive and negative patients with polymerase chain reaction. we cannot make a conclusion about a relationship between clinical course and mycobacterial DNA positivity.