Gold nanoparticules and uses in cancer Altin nanopartiküller ve kanserde kullanimlari

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DEMİRTAŞ H., ŞENGEL TÜRK C. T.

Ankara Universitesi Eczacilik Fakultesi Dergisi, cilt.45, sa.1, ss.70-95, 2021 (Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 1
  • Basım Tarihi: 2021
  • Doi Numarası: 10.33483/jfpau.773430
  • Dergi Adı: Ankara Universitesi Eczacilik Fakultesi Dergisi
  • Derginin Tarandığı İndeksler: Scopus, Central & Eastern European Academic Source (CEEAS), EMBASE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.70-95
  • Anahtar Kelimeler: Cancer, Drug delivery system, Gold nanoparticles
  • Ankara Üniversitesi Adresli: Evet

Özet

© 2021 University of Ankara. All rights reserved.Objective: Nanotechnology has become more and more potentially used in diagnosis or treatment of diseases. Gold nanoparticles (AuNP) are used in the diagnosis and treatment of various cancer types thanks to their superior properties. Within the scope of this review, general information about AuNPs, scientific studies on their use in cancer and recent developments have been presented by scanning academic databases. Result and Discussion: By means of the unique optical, electrical and physicochemical properties of AuNPs, it is used as a drug delivery system, imaging agent, photothermal therapy, photodynamic therapy and biosensor in cancer diagnosis and treatment. The fact that AuNP synthesis is easy and the nanoparticle surface is suitable for modification with many ligands provides great benefits for these applications. Thanks to these features, AuNPs come to the fore as promising systems in cancer treatment.