Human follicular fluid from pre-ovulatory follicles in patients undergoing in-vitro fertilization inhibits the in-vitro growth of gram-positive micro-organisms

Gürgan T., Urman B., Diker K., Delilbasi L., Kisnisci H.

Human Reproduction, vol.8, no.4, pp.508-510, 1993 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 4
  • Publication Date: 1993
  • Doi Number: 10.1093/oxfordjournals.humrep.a138085
  • Journal Name: Human Reproduction
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.508-510
  • Keywords: Antimicrobial activity, Follicular fluid, IVF
  • Ankara University Affiliated: No

Abstract

In this study, we assessed the antibacterial activity of human follicular fluid obtained from patients undergoing oocyte aspiration for in-vitro fertilization and embryo transfer. Gram-positive and Gram-negative microorganisms and Candida albicans were added to the follicular fluid and broth cultures which served as controls. Follicular fluid was shown to be inhibitory against Gram-positive microorganisms; this inhibition was probably due to lysosyme and progesterone. Growth of Gram-negative micro-organisms and C.albicans were, however, supported by follicular fluid incubation. © 1993 Oxford University Press.