Human follicular fluid from pre-ovulatory follicles in patients undergoing in-vitro fertilization inhibits the in-vitro growth of gram-positive micro-organisms

Gürgan T., Urman B., Diker K., Delilbasi L., Kisnisci H.

Human Reproduction, cilt.8, sa.4, ss.508-510, 1993 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 4
  • Basım Tarihi: 1993
  • Doi Numarası: 10.1093/oxfordjournals.humrep.a138085
  • Dergi Adı: Human Reproduction
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.508-510
  • Anahtar Kelimeler: Antimicrobial activity, Follicular fluid, IVF
  • Ankara Üniversitesi Adresli: Hayır

Özet

In this study, we assessed the antibacterial activity of human follicular fluid obtained from patients undergoing oocyte aspiration for in-vitro fertilization and embryo transfer. Gram-positive and Gram-negative microorganisms and Candida albicans were added to the follicular fluid and broth cultures which served as controls. Follicular fluid was shown to be inhibitory against Gram-positive microorganisms; this inhibition was probably due to lysosyme and progesterone. Growth of Gram-negative micro-organisms and C.albicans were, however, supported by follicular fluid incubation. © 1993 Oxford University Press.