Elastography and Doppler May Bring a New Perspective to TIRADS, Altering Conventional Ultrasonography Dominance

Baş H., ÜSTÜNER E., KULA S., KONCA C., DEMİRER S., ELHAN A. H.

Academic Radiology, cilt.29, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1016/j.acra.2021.02.011
  • Dergi Adı: Academic Radiology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE
  • Anahtar Kelimeler: Thyroid Nodule, Ultrasonography, Sonoelastography, Color Doppler Ultrasonography, Thyroid Imaging Reporting and Data System, SHEAR-WAVE ELASTOGRAPHY, THYROID ASSOCIATION GUIDELINES, THAN-WIDE SHAPE, DIFFERENTIAL-DIAGNOSIS, RISK STRATIFICATION, CLINICAL-PRACTICE, MALIGNANCY RISK, DATA SYSTEM, NODULES, ULTRASOUND
  • Ankara Üniversitesi Adresli: Evet

Özet

© 2021 The Association of University RadiologistsRationale and Objectives: The main aim of ultrasonography (US) examining thyroid nodules is to differentiate malignant nodules from benign nodules. Several professional societies and groups of investigators have defined guidelines such as Thyroid Imaging Reporting and Data System (TIRADS) to provide the standardized language and approach to thyroid nodules. This study is aimed to investigate the compatibility of such classification systems with the pathological diagnosis of nodules and evaluate the contribution of the Shear-wave elastography (SWE) and Doppler ultrasonography (DUS) findings. Materials and Methods: This is a prospective study. Patients with thyroid US exams between December 2017 and April 2019 were included. In the study, eligible 210 nodules from 210 patients were enrolled. For stratification, the conventional B-mode US, SWE and DUS were performed. According to Kwak, American College of Radiology (ACR), and European (EU)-TIRADS, Nodules were classified separately, and a new scoring system whose the criteria was put defined in the study has developed. Results: For SWE; Emean cut-off value was 33 kPa with a sensitivity and specificity of 95,6% (95% CI: 0,85-0,98) and 95% (95% CI:0,90-0,97) respectively (p <0.001). For spectral DUS; resistivity index (RI) cut-off value was 0.64 with a sensitivity and specificity of 73,3% (95% CI:0,59-0,83) and 80% (95% CI:0,73-0,85) respectively (p <0.001). Kwak TIRADS, American College of Radiology TIRADS, EU-TIRADS, and new system were compared by ROC curve analysis. The new system has the highest sensitivity, specificity, PPV, NPV, accuracy, and AUC compared to others. Conclusions: The new scoring system has shown that SWE and DUS findings may alter the categorization in TIRADS and increase sensitivity and specificity.