Optimizing nitric oxide production by time dependent L-arginine administration in isolated human corpus cavernosum

GÜR, SERAP; Kadowitz, Philip; Trost, Landon; Hellstrom, Wayne

doi:10.1016/j.juro.2007.05.121

Optimizing nitric oxide production by time dependent L-arginine administration in isolated human corpus cavernosum

GÜR S., Kadowitz P. J., Trost L., Hellstrom W. J. G.

JOURNAL OF UROLOGY, cilt.178, sa.4, ss.1543-1548, 2007 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 178 Sayı: 4
Basım Tarihi: 2007
Doi Numarası: 10.1016/j.juro.2007.05.121
Dergi Adı: JOURNAL OF UROLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1543-1548
Anahtar Kelimeler: penis, impotence, sildenafil, arginine, muscle relaxation, SMOOTH-MUSCLE, ERECTILE DYSFUNCTION, PENILE ERECTION, RELAXATION, KINASE, NEUROTRANSMISSION, MECHANISM, RABBIT, RAT
Ankara Üniversitesi Adresli: Evet

Özet

Purpose: We investigated the relaxant effects of repetitive administration of L-arginine, the substrate for nitric oxide, at hourly intervals and elucidated its mechanism of action in human corpus cavernosum.