A new parameter in predicting contrast-induced nephropathy: Osaka prognostic score

Özbeyaz N. B., Algül E.

REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, vol.70, no.7, pp.1-6, 2024 (SCI-Expanded)

  • Publication Type: Article / Article
  • Volume: 70 Issue: 7
  • Publication Date: 2024
  • Doi Number: 10.1590/1806-9282.20240423
  • Journal Name: REVISTA DA ASSOCIACAO MEDICA BRASILEIRA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.1-6
  • Ankara University Affiliated: Yes

Abstract

SUMMARY

OBJECTIVE: Nowadays, the frequency of complications is also increasing following the increasing frequency of coronary angiography and percutaneous 

coronary intervention. Contrast-induced nephropathy is one of the most common of these complications. This study aimed to investigate the 

relationship between the Osaka prognostic score, which has previously been shown to have prognostic importance in gastrointestinal malignancies, 

and the development of contrast-induced nephropathy.

METHODS: The study retrospectively examined the data of 1,498 patients who underwent coronary angiography and percutaneous coronary 

intervention due to acute coronary syndrome between 2018 and 2023. Demographic characteristics and laboratory findings were retrospectively 

collected from patients’ charts and electronic medical records.

RESULTS: Osaka prognostic score (0.84±0.25 vs. 2.2±0.32, p<0.001) was higher in patients who developed contrast-induced nephropathy. Also, Osaka 

prognostic score [OR 2.161 95%CI (1.101–4.241), p<0.001] was found to be an independent risk factor along with age, diabetes mellitus, systolic 

pulmonary artery pressure, hemoglobin, hemoglobin, C-reactive protein, albumin, N-terminal brain natriuretic peptide, and systemic immuneinflammation index. The receiver operating characteristic curve showed that the optimal cutoff value of Osaka prognostic score to predict the 

development of contrast-induced nephropathy was 1.5, with a sensitivity of 83.4 and a specificity of 65.9% [area under the curve: 0.874 (95%CI: 

0.850–0.897, p≤0.001)].

CONCLUSION: Osaka prognostic score may be an easily calculable, user-friendly, and useful parameter to predict the development of contrastinduced nephropathy in patients undergoing percutaneous coronary intervention after acute coronary syndromes.

KEYWORDS: Osaka prognostic score. Inflammation. Nutrition. Contrast‑induced nephropathy. Acute coronary syndrome. Percutaneous coronary intervention