Neurodevelopmental problems of very low birth weight premature infants and factors affecting neurological morbidity Çok düşük doǧum aǧirlıklı erken doǧmuş bebeklerin nörogelişimsel sorunları ve nörolojik hastaliǧa etki eden etmenlerin araştırılması


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Göçer C., Kavuncuoǧlu S., Arslan G., Ertem L., Özbek S., Öztüregen E., ...More

Turk Pediatri Arsivi, vol.46, no.3, pp.207-214, 2011 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 3
  • Publication Date: 2011
  • Doi Number: 10.4274/tpa.46.76
  • Journal Name: Turk Pediatri Arsivi
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.207-214
  • Keywords: Cerebral palsy, Denver developmental screening test, Neurodevelopmental outcome, Prematurity
  • Ankara University Affiliated: Yes

Abstract

Objective: To evaluate neurodevelopmental outcome of prematures born less than 32 gestational weeks and /or with very low birth weight (<1500 g) at the age of three. Material and Methods: In this study neurodevelopmental characteristics (used Denver II developmental screening test, DGTT II) and neurological sequelae (Amiel Tison) were examined retrospectively. Results: Seventeen hundred infants 27-42 (mean:35,8-2,3) months of age were evaluated. There were 57 female, 60 male patients and mean birth weight and gestational age were: 1271±22,09 gr and 31± 2,1 weeks respectively. Most important acute morbidities were as follows: Respiratory distress syndrome (21%), bronchopulmonary dysplasia (%8), severe retinopathy of prematurity (5%), sepsis (21%), severe intraventricular hemorrhage (7%), Apgar score <6 (24%). 9,4% patients had major neurological sequelae; ten cases had cerebral palsy, five had hydrocephalus and blindness was recorde in two cases. Denver II Developmental screening Test was abnormal in 23% of cases. Conclusion: Our neurodevelopmental assessment results were similar to the literature. One of the most important risk factors, in neurodevelopmental retardation was transport.