Oral probiotics: Lactobacillus sporogenes for prevention of necrotizing enterocolitis in very low-birth weight infants: a randomized, controlled trial

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Sari F. N., Dizdar E. A., Oguz S., Erdeve Ö., Uras N., Dilmen U.

EUROPEAN JOURNAL OF CLINICAL NUTRITION, cilt.65, sa.4, ss.434-439, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 65 Sayı: 4
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1038/ejcn.2010.278
  • Dergi Adı: EUROPEAN JOURNAL OF CLINICAL NUTRITION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.434-439
  • Anahtar Kelimeler: necrotizing enterocolitis, preterm infant, probiotics, PRETERM INFANTS, COLONIZATION, SEPSIS, INTESTINE
  • Ankara Üniversitesi Adresli: Evet

Özet

Background/Objective: The identification of probiotic species involved in gut homeostasis and their potential therapeutic benefits have led to an interest in their use for preventing necrotizing enterocolitis (NEC). Although bifidobacterium and lactobacilli sp. have been used to reduce the incidence of NEC in clinical trials. Lactobacillus sporogenes has not been used in the prevention of NEC in very low-birth weight infants yet. The objective of this study was to evaluate the efficacy of orally administered L sporogenes in reducing the incidence and severity of NEC in very low-birth weight (VLBW) infants.